Scientists say they've reversed brain aging in mice with a nasal spray
bookmtn
58 points
27 comments
May 27, 2026
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Discussion Highlights (11 comments)
wizardforhire
Was looking for the “in mice” in this article and found none… anybody got a link to the paper please
kurthr
The source paper: https://isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev...
trodney
Excellent news if you're a mouse.
instagib
“While additional research is still needed before the treatment could be tested in humans, the study offers a striking possibility.” (In mice)
CoastalCoder
Algernon for Flowers.
delichon
I'm afraid of the result if we take someone wrapped in a comforting haze of dementia (I'm getting there) and force them into cold harsh reality. It may be as welcome a sobriety to an alcoholic. If the insurance stops paying does it become Flowers for Algernon? We have several drugs that emulate dementia in various ways and call them recreational.
qnleigh
> Behavioral testing showed that treated models performed significantly better on memory and recognition tasks. "Treated models" - it sounds like they're trying really hard to hide the fact that this was all in mice. From the paper: > Therefore, using a mouse model, this study investigated whether IN administration of hiPSC-NSC-EVs in late middle age can significantly reduce oxidative stress and curb microglia-mediated neuroinflammaging in the hippocampus. Cool! But please be honest in your press releases.
Morromist
Imagine the political implications of this if it actually worked.
dolphinscorpion
These billionaire mice are funding this research; humans should do the same
molticrystal
edit: admin dang has fixed the title I always interpret the rule [0] "Otherwise please use the original title, unless it is misleading or linkbait; don't editorialize." as applying to stories like this one. Adding the words [in mice] would not only be the acceptable exception the rule is referring to, but probably necessary. This would align the title properly with the article contents and avoid giving people false expectations about human results. [0] https://news.ycombinator.com/newsguidelines.html
Zealotux
This headline is keeping me young because I keep reading it every five years or so.