Novo Nordisk, Eli Lilly Report GLP-1 Signals of Slowed Biological Aging at ARDD

ChrisArchitect

Related: GLP-1 may slow biological aging https://news.ycombinator.com/item?id=50132328

xnx

Many here have expressed skepticism at GLP1s because they don't require the personal discipline of caloric deficit and might have unknown side effects. So far, all the unknown side effects I've read about have been like this.

nozzlegear

Sign me up for this miracle drug already.

hiop

TLDR; being fat accelerates aging

sublinear

> Vadim Gladyshev, a Harvard biologist who assisted Novo with its molecular measurements, said: "In an unhealthy population, I do think it's an anti-aging drug. But in a healthy population, no one knows." I'm glad the article actually said what we're all thinking. It makes perfect sense that managing blood glucose and a healthier diet/weight would "slow biological aging" regardless of how it was done. I'm only skeptical of GLP-1 because it seems unnecessary, but if it helps some people I guess it's their choice.

Gathering6678

I use GLP-1 to control my weight, which was obese according to the BMI before taking it. I don't really care about the other benefits that may or may not be true or relevant to me, but I am deeply convinced that controlling my weight is massively beneficial for my long-term health and completely overweighs all my concerns about side effects.

grokgrok

The surprise would be if it didn't show reduced aging, calorie deficit diets are well established to produce this effect.

tgsovlerkhgsel

I've seen semi-hidden advertising for GLP-1 drugs in the form of "you wouldn't blame people for being sick, so don't blame them for being obese and start treating obesity like any other illness". I don't know why this sits so wrong with me - the message itself is legit but it's clearly GLP-1 advertising. Maybe because overt advertising would be illegal in the countries where I saw this?