Moderna, Merck Vaccine Succeeds in Preventing Melanoma from Returning

marc__1 19 points 3 comments August 19, 2026
www.wsj.com · View on Hacker News

Discussion Highlights (3 comments)

cebert

Gift link: https://www.wsj.com/health/pharma/moderna-merck-vaccine-succ...

rvz

The news here is significant and this took decades of studies and research to validate this. Well done to Merck and Moderna.

root-parent

There is nothing to see here yet other than their stock popped 50%. Based on unpublished data... - The initial 49% number comes from a very small phase 2 trial that had only 157 patients. And their original p-value was 0.053 - This phase 3 news so far is nothing more than a press release. They have not published hazard ratio, or confidence interval, their event counts or survival curves. - They met the endppoint as used in the press release means nothing, until they publish the actual 3 data, so my money is at the end this will be a kind of marginal effect that researchers will struggle to reproduce for years This is the type of study that will take 3 to 4 years to validate or dismiss, in the meanwhile stock is up 50%....

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