MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

throwaway12pol

Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!

analog8374

"Today a young man on acid realized that all matter is merely energy condensed to a slow vibration, that we are all one consciousness experiencing itself subjectively, there is no such thing as death, life is only a dream, and we are the imagination of ourselves. Here's Tom with the weather." -Bill Hicks

Rygian

The "surprising way" is by using a derivate of LSD. I'd argue that the surprise is rather on this: "In clinical trials, a single dose significantly outperformed standard treatments, offering hope to those who have found little relief elsewhere."

kykat

It seems like every few weeks there's an article on how drugs are amazing hitting the front-page.

kunley

It is tragically funny to consider linking quietness of mind with LSD. It is everything but quiet

PowerElectronix

"Side effects were mild or moderatr and included hallucinations..." Yeah....

OutOfHere

Of course they want to repackage a cheaply synthesized substance at 100-1000x the costs even though the original likely works just as well. That's pharma for you.

khelavastr

This reflects a longstanding...essentially conspiracy...to suppress attention to 5HT2A-based neural regulation because it sheds such poor light on SSRIs

tim-projects

I'd argue that the results might not be from the drugs but from the fact that they were heavily monitored by other humans. It's not the drugs that people with high anxiety need, it's people giving them attention and caring for them. These experiments need a control where they just take the drug and they don't have medical staff around.

steve-atx-7600

I’d be afraid of a treatment like this where you’re sort of different after one treatment. From experience taking ssris, I took one one that worked so well that I had to stop taking it because it removed stress to the extent that I wouldn’t get to class on time or get my homework done before deadlines. Eventually I found a medicine that worked for me. But, if there’s a “before” vs “after” one shot treatment, you have to hope the new you is the one you want assuming you could be stuck there permanently.

catigula

These psychedelic treatments always have substantial limitations, and this is no different; 1. Low volume cohort i.e. 40 participants per dose group 2. Industry sponsored study i.e. MindMed. 3. Think about it; how do you blind psychedelics? It's pretty obvious you're on one when you take it.

rdtsc

> It's usually treated with medications like Zoloft and Paxil that boost and stabilize the neurotransmitter serotonin, leading to reduced anxiety and enhanced emotional well-being How do figure the boost and stabilize part for a patient? Do they take samples of neurotransmitters in the spinal fluid before and after and looking for neurotransmitter concentrations?

butlike

At the risk of sounding like an imbecile, can I ask why LSD-25 can't be the pharmaceutical form of LSD?

simulator5g

This will be like legal weed. Assuming it isn't already, the pharma bean counters will turn it into something awful.