Medici family mystery may be solved after more than 400 years
effects
102 points
26 comments
July 22, 2026
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Discussion Highlights (6 comments)
bell-cot
tl;dr; - Scientists did DNA testing on the remains of the Grand Duke and his wife, and found malaria. The rival theory is poisoning by the relative who was next in line for the Ducal throne. HOWEVER, this test result solves nothing: > But is there any guarantee that Francesco was not also poisoned? > “Perhaps not,” Ochoa said, “but the genetic evidence presented in our study decreases the margin for speculation.” > Gisella Caccone, a senior research scientist also at Yale and a study coauthor, agrees. “We can say that they had malaria, we cannot say that they were not poisoned as well,” Caccone said in an email.
asdfman123
Nice work science, but 400 years is a long time to hold onto old grudges. I go by what the "Good Book" says and "forgive and forget." (sorry guys channeling my ken m)
jjmarr
My family has spent centuries marrying into an alternative claimant to the Grand Duke of Tuscany who did not inherit through Ferdinando I. We were planning to use this as an excuse to invade Italy and put the scion of our own dynasty on the throne and establish ourselves as royalty in the annals of history. Unfortunately, this + the unification of Italy may have irredeemably foiled our plan. Not sure what to do now, should I find a wife with a better claim?
DaveZale
so interesting. I worked for a very small company getting funding by the Medici Fund a while back. First I ever heard of the name. So much intrigue in the past. Guys like Montaigne were said to have "food tasters" to sample the goods before they ate themselves. As a career trace analytical chemist, I can tell you for sure, that weird poisonings are so much less likely to occur now, because of the probability of detection. That's a little comforting. The same goes for the food supply. Mechanisms are in place to rapidly detect deliberately placed poisons.
yieldcrv
what a mess, what is the significance of resolving this? land claims? title? access to frozen assets? recarving borders? treaties?
efebarlas
What's this one? Fable or Sol?