Lyme Disease Vaccine Candidate Demonstrates Strong Efficacy in Phase 3 Trial

mhb 45 points 3 comments March 23, 2026
www.pfizer.com · View on Hacker News

Discussion Highlights (3 comments)

bethekidyouwant

“ As the tick feeds on the vaccinated person, these antibodies are ingested by the tick as part of its blood meal. Binding of vaccine-induced antibodies to OspA on Borrelia inside the tick inhibits the bacterium’s ability to leave the tick” What an odd mechanism of action. I did not see any mention of long-term efficacy for something that would require our blood serum to have. I imagine, indefinitely, a significant amount of antibodies circulating in our blood.

redeeman

now imagine if the US government had simply not made and released this disease. but no, thats too much to ask. anyone involved should be found, even if 90 years old, and put to justice for it.

balderdash

I wonder what the efficacy is > a month (maybe I missed it).

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