Coffee appears to rewire the gut-brain connection

loh 13 points 10 comments May 04, 2026
www.sciencedaily.com · View on Hacker News

Discussion Highlights (8 comments)

gnabgib

Seems similar to last year's Coffee drinking habits may greatly impact makeup of gut biome (48 points, 24 comments) https://news.ycombinator.com/item?id=42251379 Last year's wasn't funded by Scientific Information on Coffee This paper (open): https://www.nature.com/articles/s41467-026-71264-8 Paper from 2024 (open): https://www.nature.com/articles/s41564-024-01858-9

vivzkestrel

so how come IBS-C has a problem with coffee then?

cadamsdotcom

> coffee was gradually reintroduced without participants knowing whether they were drinking caffeinated or decaffeinated coffee. Half received decaf, while the others consumed regular coffee. Both groups reported improvements in mood, including lower levels of stress, depression, and impulsivity. These results suggest that coffee can enhance mood even without caffeine. Or it just suggests people are creatures of habit and comforts :)

dartharva

> ..The findings, published in Nature Communications and supported by the Institute for Scientific Information on Coffee (ISIC) .. Hmm

bulbar

Comes the newest research focus with a decline in caffeine consumption (in the younger generation)? Is this part of a strategic move to reframe coffee as a general 'feel good' product instead of the efficiency connotation it has today?

Tsarp

I indulge in coffee quite a bit too. But the funding chain here is - Major coffee companies illy | JDE Peet's | Lavazza | Paulig | Tchibo ↓ Institute for Scientific Information on Coffee (ISIC) ↓ UCC/APC Microbiome Ireland study ↓ UCC press release → ScienceDaily article

ZYZ64738

There are many ways to make coffee, with various options for additions like milk (including plant-based milk) and sugar, as well as flavorings... Don't these have any effect at all?

wojciii

Sure. I have stopped drinking coffee because it increases stress and anxiety for me. This is the opposite of what the scientists have found according to the article. I have a feeling that everything about food and how people digest it are dependent on the person and any generalized articles like this are completely useless.

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