Coffee appears to rewire the gut-brain connection
loh
13 points
10 comments
May 04, 2026
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Discussion Highlights (8 comments)
gnabgib
Seems similar to last year's Coffee drinking habits may greatly impact makeup of gut biome (48 points, 24 comments) https://news.ycombinator.com/item?id=42251379 Last year's wasn't funded by Scientific Information on Coffee This paper (open): https://www.nature.com/articles/s41467-026-71264-8 Paper from 2024 (open): https://www.nature.com/articles/s41564-024-01858-9
vivzkestrel
so how come IBS-C has a problem with coffee then?
cadamsdotcom
> coffee was gradually reintroduced without participants knowing whether they were drinking caffeinated or decaffeinated coffee. Half received decaf, while the others consumed regular coffee. Both groups reported improvements in mood, including lower levels of stress, depression, and impulsivity. These results suggest that coffee can enhance mood even without caffeine. Or it just suggests people are creatures of habit and comforts :)
dartharva
> ..The findings, published in Nature Communications and supported by the Institute for Scientific Information on Coffee (ISIC) .. Hmm
bulbar
Comes the newest research focus with a decline in caffeine consumption (in the younger generation)? Is this part of a strategic move to reframe coffee as a general 'feel good' product instead of the efficiency connotation it has today?
Tsarp
I indulge in coffee quite a bit too. But the funding chain here is - Major coffee companies illy | JDE Peet's | Lavazza | Paulig | Tchibo ↓ Institute for Scientific Information on Coffee (ISIC) ↓ UCC/APC Microbiome Ireland study ↓ UCC press release → ScienceDaily article
ZYZ64738
There are many ways to make coffee, with various options for additions like milk (including plant-based milk) and sugar, as well as flavorings... Don't these have any effect at all?
wojciii
Sure. I have stopped drinking coffee because it increases stress and anxiety for me. This is the opposite of what the scientists have found according to the article. I have a feeling that everything about food and how people digest it are dependent on the person and any generalized articles like this are completely useless.