Aspartame is not that bad? (2022)
pHequals7
118 points
243 comments
April 24, 2026
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Discussion Highlights (20 comments)
pfdietz
Sucralose-6-acetate, however, an impurity found in sucralose and produced in vivo from sucralose, is genotoxic. https://pubmed.ncbi.nlm.nih.gov/37246822/ I would avoid sucralose. I have a suspicion it may be responsible for the observed increase in colon cancer in younger age groups.
rcxdude
Yeah, it's a frequent target of the naturalistic fallacy. But to me the most honest criticism of it is not liking the taste. Health-wise, almost certainly better than the sugar it's replacing.
misthop
It might not be bad for you, but it tastes like crap
hawk_
An important missed angle is the effect of artificial sweeteners on gut microbiome. They cause intestinal inflammation which is relevant for IBD sufferers. My take is that I don't miss out on much by being conservative with food, as we still don't understand these complex interactions well enough. What's the harm in sticking to a balanced whole diet of ingredients that were available to our ancestors 200years or more ago.
GolfPopper
It's a reliable migraine trigger for meyself, and my nephew. That makes it bad for us.
bronlund
It is bad. Don't belive the hype. Just the simple fact that it has a sweet taste, but contains no sugar, disturbs the body's natural production of insulin.
lormayna
In Italy we have an "indipendent research lab" that become really famous for a study that demonstrates that aspartame may cause cancer. The same institute published few years later a study about 5G emissions that may cause cancer.
mmastrac
I don't understand how prevalent Aspartame and other artificial sweeteners are when they taste so bad. They don't even taste sweet to me, just "wrong" in a way that permeates my entire mouth. Is this a genetic thing?
swiftcoder
> The history of aspartame and the FDA is contentious and sort of infuriating Is it? They've been dealing with conspiracy theorists on this topic for more than half a century (it was initially approved as a tabletop sweetener back in 1974), including extensive public hearings in the 1980s. There is no more thoroughly studied or litigated food additive in the department's history.
fabioyy
migraine trigger for me too
m4ck_
It's probably not great if you're drinking dozens of cans of sugar free soda every day. All I really know is don't take health advice from influencers, especially if they're selling something, and don't take health advice from people who support deregulation (less industry transparency, oversight, and consequences won't make food or anything safer.)
cael450
> Half of the world’s aspartame is made by Ajinomoto of Tokyo—the same company that first brought us MSG back in 1909. There is nothing wrong with MSG either
1970-01-01
Fact 5 is a false fact. Taking facts 1-4 into consideration with the (0th?) fact that it is considered the most studied ingredient is enough evidence. This is how scientists come to a consensus. Going beyond that is obscene to science.
nicole_express
Honestly I believe there's a puritan streak in the aspartame controversy; you don't deserve to experience sweet taste if you're trying to avoid sugar, you need to suffer for your diet, and it's unfair to have a zero-calorie soda that tastes good. I could be convinced otherwise by data, but when I'm seeing decades of attempts to prove it's dangerous and none actually pan out, I'm not going to feel bad about drinking a few diet cokes a day.
Lerc
I don't drink things with Aspartame because it makes me feel queasy. I don't know of any mechanism that causes that effect. Occasionally I encounter something that I would not have expected to contain Aspartame that I notice the feeling before I have even considered the possibility that it might be present. I take that as a sign that it is not psychological.
goolz
Even so, it has a weird aftertaste that lingers on the palette. All sugar-free elixirs I have found to be subpar.
paulinho1
I think it's just human nature. We assume anything good has to have a catch. Diet Coke feels like that to me
cestith
The one we’re trying to avoid the most in my household is sucralose. Genotoxicity and upregulating inflammation and oxidative stress are bad things. Accumulating unchanged in the environment and resisting biodegradation is a bad thing. https://pmc.ncbi.nlm.nih.gov/articles/PMC12251854/
happygreybanana
There's also an ever-escalating sweetness issue. When fresh fruit was plenty sweet enough and you get used to this level of sweetness, everything else seems to taste pretty bland. If this becomes the normal (I suspect it kind of has), everything gets sweetened; yogurts, crackers, bread, etc. The method those things get sweetened could be aspartame, but many will not be.
jiaosdjf
So basically there's no scientific consensus either way, there's no tradition of using it and there are extreme commercial incentives for harm so it's a no from me