AI discovery reveals DNA isn’t locked away in cells after all

rolph

“The conception before was that, when it came to nucleosomes, genes were either turned on or off, but we’re finding it’s more like a volume dial,” this is not a new paradigm. this was apparent in the late 80s. modulation of DNA / nucleosomal binding affinity, is a known epigenetic mechanism for the last 35 years. DNA expressivity is not digital, its result of many affinity based interactions over time contributing to a summary result in the form of conformational change or rate of reaction.

nrds

So you're telling me that cells use an attention system for DNA?

marshray

After reading that amazing title, I skimmed the whole article several times looking for the part about DNA existing outside the cells.