Advancing human gut microbiota research by considering gut transit time (2023)

mikhael 99 points 78 comments April 20, 2026
gut.bmj.com · View on Hacker News

Discussion Highlights (20 comments)

devolving-dev

I wonder what this means for GLP 1 drugs that slow digestion.

hhh

And if I flip flop between both?

flossly

I did quite some experimenting with this. Fruit moves fastest and green leaves. Meat, cheese, oil and fats slowest. But we often eat combinations: and the slowest component of your food determines the speed of the whole. Also: it's a one lane road and "over taking" is not possible. So, eating a fast moving meal after a slow moving meal results in the fast mover getting stuck behind the slow mover. Hence I start my day without and slow food (only fruit, herbs, green leaves, spices, ginger => usually a smoothy); and end the day with slow food (oily food, nuts, seeds, beans; usually combined with green leaves as we need a lot green leaves). YMMV

cess11

https://gut.bmj.com/content/72/1/180 The study. It basically says that this is something one perhaps should consider in clinical settings and that the speed of fecal matter might be a worthwhile direction for future inquiry. "Altogether, a better understanding of the complex, bidirectional interactions between the gut microbiota and transit time is required to better understand gut microbiome variations in health and disease." It does not say 'this is a sign of health and that is not'.

beardyw

If the writer ingested a lot, very little came out.

sph

I guess with my IBS I should be the healthiest person around.

jonatron

I'm surprised there's no mention of hot drinks in the morning.

feverzsj

Eat lots of fibers and water, and you'll poop like a cow.

pawelduda

Sooo.... Another reason to drink coffee/yerba mate? Although the latter also supposedly stimulates release of GLP1, which slows down "the release"

fibermaxxx

More fiber, more plants. I know individuals that eat "only vegetable on the burger" Oats, grits, or smoothie for early day Mine:Fruit smoothie with oats Starches, leafy greens, for midday Mine:roasted sweet potato on a salad Legumes and tree nuts for dinna Mine:Chickpea sauce over roasted veggies with pasta, or cashews. The goal is more than 13 plants a day and your movement will be very consistent

iszomer

Consumption of dairy and products are a relatively fast and painful solution for personal system purges within 30m but entirely depends on how processed they are.

phyzix5761

I wonder how Ozempic affects this because it slows down gastric emptying.

Grp1

this post needs an enema

bregma

I find I can't keep it down for more than a few minutes. I guess I can eat all the poop I want and stay healthy then?

dustractor

This is why I suspect that GLP-1 agonist medications have the potential to cause a cascade of negative consequences for the health of some people. One of the mechanisms is slowed gastric emptying which leads to decreased motility of the small intestine as a side effect. They do tell people to drink more water to counteract this. It just seems like trading one set of problems for another so hopefully doctor and patient will carefully weigh the benefits versus the risks. We shall see.

Qem

I wonder if this explains in part the purported health benefits from cofee. One thing people claim makes hard to quit cofee habit it's that they can't take a shit in the morning anymore.

deepsun

"Linked" not "caused". So it may be that someone with Parkinson's just happen to have slower rates.

fny

Headline is megaclickbait. The research is about how healthier gut microbiomes correlate with improved pooping and nothing about how it impacts your health.

mplanchard

The article is open access, I don’t see any reason to prefer the dumbed-down narrative summary: https://gut.bmj.com/content/72/1/180

fellowniusmonk

I've been using 1/4cup ground hulled barley and 20-32oz of greek yogurt, with a bit of craisins and pecans as my base for the last several years, my gut now chews through everything and output is consistent and homogeneous. You gotta lay down a fermentation base.

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